diff --git a/pkgs/development/libraries/ffmpeg/generic.nix b/pkgs/development/libraries/ffmpeg/generic.nix
index 13872b7e4140..7e7519567883 100644
--- a/pkgs/development/libraries/ffmpeg/generic.nix
+++ b/pkgs/development/libraries/ffmpeg/generic.nix
@@ -59,7 +59,7 @@
   withChromaprint ? withFullDeps, # Audio fingerprinting
   withCodec2 ? withFullDeps, # codec2 en/decoding
   withCuda ? withFullDeps && withNvcodec,
-  withCudaLLVM ? withHeadlessDeps,
+  withCudaLLVM ? withHeadlessDeps && !stdenv.hostPlatform.isDarwin, # Cuda isn’t supported on Darwin
   withCudaNVCC ? withFullDeps && withUnfree && config.cudaSupport,
   withCuvid ? withHeadlessDeps && withNvcodec,
   withDav1d ? withHeadlessDeps, # AV1 decoder (focused on speed and correctness)