diff --git a/pkgs/development/python-modules/xmlsec/default.nix b/pkgs/development/python-modules/xmlsec/default.nix
index e1178ff3058f..81f4571b32e6 100644
--- a/pkgs/development/python-modules/xmlsec/default.nix
+++ b/pkgs/development/python-modules/xmlsec/default.nix
@@ -40,6 +40,7 @@ buildPythonPackage (finalAttrs: {
 
   postPatch = ''
     substituteInPlace pyproject.toml \
+      --replace-fail "lxml==" "lxml>=" \
       --replace-fail "setuptools==" "setuptools>="
   '';