diff --git a/pkgs/by-name/gr/grpc/package.nix b/pkgs/by-name/gr/grpc/package.nix
index fd682d3b0516..84e80bfc5b7d 100644
--- a/pkgs/by-name/gr/grpc/package.nix
+++ b/pkgs/by-name/gr/grpc/package.nix
@@ -25,7 +25,7 @@
 # nixpkgs-update: no auto update
 stdenv.mkDerivation (finalAttrs: {
   pname = "grpc";
-  version = "1.80.0"; # N.B: if you change this, please update:
+  version = "1.81.0"; # N.B: if you change this, please update:
   # pythonPackages.grpcio
   # pythonPackages.grpcio-channelz
   # pythonPackages.grpcio-health-checking
@@ -38,7 +38,7 @@ stdenv.mkDerivation (finalAttrs: {
     owner = "grpc";
     repo = "grpc";
     tag = "v${finalAttrs.version}";
-    hash = "sha256-/dpTRG5JcZY2VAsqOYNIpFW7ouSy/eC2STulP7qdSYg=";
+    hash = "sha256-o1wfHrgD2VE6HcPPEWQPQZXrMh+8+GNoUjbCQoRlIWg=";
     fetchSubmodules = true;
   };
 
diff --git a/pkgs/development/python-modules/grpcio-channelz/default.nix b/pkgs/development/python-modules/grpcio-channelz/default.nix
index 028c63669ca3..634811c727e9 100644
--- a/pkgs/development/python-modules/grpcio-channelz/default.nix
+++ b/pkgs/development/python-modules/grpcio-channelz/default.nix
@@ -12,13 +12,13 @@
 # nixpkgs-update: no auto update
 buildPythonPackage rec {
   pname = "grpcio-channelz";
-  version = "1.80.0";
+  version = "1.81.0";
   pyproject = true;
 
   src = fetchPypi {
     pname = "grpcio_channelz";
     inherit version;
-    hash = "sha256-fs6As480ti6Q5uHFqghYXwwPE8GpyI6vdNioZxw6n6E=";
+    hash = "sha256-V6Gr5QURNJv9iafEJtHbaRmOLJzUcbr2wNVgbDTbmt8=";
   };
 
   build-system = [ setuptools ];
diff --git a/pkgs/development/python-modules/grpcio-health-checking/default.nix b/pkgs/development/python-modules/grpcio-health-checking/default.nix
index 2db14472125a..3d65fef2e464 100644
--- a/pkgs/development/python-modules/grpcio-health-checking/default.nix
+++ b/pkgs/development/python-modules/grpcio-health-checking/default.nix
@@ -11,13 +11,13 @@
 # nixpkgs-update: no auto update
 buildPythonPackage rec {
   pname = "grpcio-health-checking";
-  version = "1.80.0";
+  version = "1.81.0";
   format = "setuptools";
 
   src = fetchPypi {
     pname = "grpcio_health_checking";
     inherit version;
-    hash = "sha256-LMXwi8i4FrhlWrb1nHFFAGO6IHZtMeIaST6RLjVgyLE=";
+    hash = "sha256-CfMWdPGs3PIUvE5kDru77xZbB3of1kg0eVGW1Sv9zjk=";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/grpcio-reflection/default.nix b/pkgs/development/python-modules/grpcio-reflection/default.nix
index 914cffe15618..87e145bb3513 100644
--- a/pkgs/development/python-modules/grpcio-reflection/default.nix
+++ b/pkgs/development/python-modules/grpcio-reflection/default.nix
@@ -12,13 +12,13 @@
 # nixpkgs-update: no auto update
 buildPythonPackage rec {
   pname = "grpcio-reflection";
-  version = "1.80.0";
+  version = "1.81.0";
   pyproject = true;
 
   src = fetchPypi {
     pname = "grpcio_reflection";
     inherit version;
-    hash = "sha256-6cdqq8QyQnmUW3C8dqPUG8T5OWv/zxz8EBGlccLFYiE=";
+    hash = "sha256-UZHbeqbKsbaYGwh5+kT9zdQ7pkTwMBxAuXb4E+tO/wY=";
   };
 
   build-system = [ setuptools ];
diff --git a/pkgs/development/python-modules/grpcio-status/default.nix b/pkgs/development/python-modules/grpcio-status/default.nix
index a4ebf1aaf5a2..03c03473d5ad 100644
--- a/pkgs/development/python-modules/grpcio-status/default.nix
+++ b/pkgs/development/python-modules/grpcio-status/default.nix
@@ -12,13 +12,13 @@
 # nixpkgs-update: no auto update
 buildPythonPackage rec {
   pname = "grpcio-status";
-  version = "1.80.0";
+  version = "1.81.0";
   format = "setuptools";
 
   src = fetchPypi {
     pname = "grpcio_status";
     inherit version;
-    hash = "sha256-33OAKkyJo+qIqir/lx6Ib8zOFivC5lEUCLPWehRDgc0=";
+    hash = "sha256-tv6XiM/dHw9jwFKKHgv9tB6P8Fg+kg0tjoiIWYwBu2k=";
   };
 
   postPatch = ''
diff --git a/pkgs/development/python-modules/grpcio-testing/default.nix b/pkgs/development/python-modules/grpcio-testing/default.nix
index 812e24eaf438..b3f68350d32f 100644
--- a/pkgs/development/python-modules/grpcio-testing/default.nix
+++ b/pkgs/development/python-modules/grpcio-testing/default.nix
@@ -12,13 +12,13 @@
 # nixpkgs-update: no auto update
 buildPythonPackage rec {
   pname = "grpcio-testing";
-  version = "1.80.0";
+  version = "1.81.0";
   pyproject = true;
 
   src = fetchPypi {
     pname = "grpcio_testing";
     inherit version;
-    hash = "sha256-+1rVfED/36l3MEPfo46MN3Oa+ONHHxZwoh54BRzRmv0=";
+    hash = "sha256-MjcL3/wM0Jq63pKP2ID5Gb8HCv5dASot4UEkJ7LcGSE=";
   };
 
   postPatch = ''
diff --git a/pkgs/development/python-modules/grpcio-tools/default.nix b/pkgs/development/python-modules/grpcio-tools/default.nix
index d079a2447a3f..bf74b27fcea2 100644
--- a/pkgs/development/python-modules/grpcio-tools/default.nix
+++ b/pkgs/development/python-modules/grpcio-tools/default.nix
@@ -13,13 +13,13 @@
 # nixpkgs-update: no auto update
 buildPythonPackage rec {
   pname = "grpcio-tools";
-  version = "1.80.0";
+  version = "1.81.0";
   pyproject = true;
 
   src = fetchPypi {
     pname = "grpcio_tools";
     inherit version;
-    hash = "sha256-JgUrGcbODc9S0QJElq6j4r36hkFZ8G3HuXsi0EGpSyY=";
+    hash = "sha256-BzPXc+yoy0YfTyobecZMEj25ZhvkGwgYS4FJeyuZHMs=";
   };
 
   postPatch = ''
diff --git a/pkgs/development/python-modules/grpcio/default.nix b/pkgs/development/python-modules/grpcio/default.nix
index 880782e6c683..7b786ec380ba 100644
--- a/pkgs/development/python-modules/grpcio/default.nix
+++ b/pkgs/development/python-modules/grpcio/default.nix
@@ -18,12 +18,12 @@
 # nixpkgs-update: no auto update
 buildPythonPackage rec {
   pname = "grpcio";
-  version = "1.80.0";
+  version = "1.81.0";
   pyproject = true;
 
   src = fetchPypi {
     inherit pname version;
-    hash = "sha256-KayhXt0GiMIroB18wBywANcrIDP0o8cqgaGbVv0UMlc=";
+    hash = "sha256-pazX79Ox/ptOsLyqoVB+7WigrQZ4tlTD97Rk35up3KU=";
   };
 
   postPatch = ''